Description
| 抗体名: | TRIM15 Antibody (PACO42142) |
| 抗体コード: | PACO42142 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Tripartite motif-containing protein 15 protein (122-387AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: TRIM15 antibody at 2µg/ml. Lane 1: Jurkat whole cell lysate. Lane 2: Hela whole cell lysate. Lane 3: HepG2 whole cell lysate. Lane 4: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 53, 13 kDa. Observed band size: 53 kDa. |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO42142 at dilution of 1:100. |
| バックグラウンド: | innate immune response, mesodermal cell fate determination, negative regulation of intracellular transport of viral material, negative regulation of viral release from host cell, positive regulation of NF-kappaB transcription factor activity, positive regulation of RIG-I signaling pathway, positive regulation of sequence-specific DNA binding transcription factor activity, positive regulation of type I interferon production |
| シノニム: | Tripartite motif-containing protein 15 (RING finger protein 93) (Zinc finger protein 178) (Zinc finger protein B7), TRIM15, RNF93 ZNF178 ZNFB7 |
| UniProt Protein Function: | TRIM15: is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Cell development/differentiation; Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 6p22.1 Molecular Function:protein binding Biological Process: activation of NF-kappaB transcription factor; innate immune response; mesodermal cell fate determination; positive regulation of interferon type I production; positive regulation of transcription factor activity |
| NCBI Summary: | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9C019 |
| NCBI GenInfo Identifier: | 25009482 |
| NCBI Gene ID: | 89870 |
| NCBI Accession: | Q9C019.1 |
| UniProt Secondary Accession: | Q9C019,O95604, Q8IUX9, Q9C018, A2BEC9, |
| UniProt Related Accession: | Q9C019 |
| Molecular Weight: | 52kDa |
| NCBI Full Name: | Tripartite motif-containing protein 15 |
| NCBI Synonym Full Names: | tripartite motif containing 15 |
| NCBI Official Symbol: | TRIM15 |
| NCBI Official Synonym Symbols: | RNF93; ZNFB7; ZNF178 |
| NCBI Protein Information: | tripartite motif-containing protein 15 |
| UniProt Protein Name: | Tripartite motif-containing protein 15 |
| UniProt Synonym Protein Names: | RING finger protein 93; Zinc finger protein 178; Zinc finger protein B7 |
| Protein Family: | Tripartite motif-containing protein |
| UniProt Gene Name: | TRIM15 |
