The TRAP1 Polyclonal Antibody (CAB4378) is a valuable tool for research involving TRAP1, a mitochondrial chaperone protein with a key role in regulating cellular metabolism and stress responses. This antibody, developed using rabbit immunization, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications. By specifically binding to TRAP1 protein, this antibody allows for precise detection and analysis in various cell types, facilitating studies in mitochondrial biology and cancer research.TRAP1, also known as tumor necrosis factor type 1 receptor-associated protein, is a crucial player in maintaining mitochondrial function and protecting cells from stress-induced damage.
Its involvement in cellular processes such as apoptosis, proliferation, and energy metabolism highlights its potential as a therapeutic target for diseases like cancer, neurodegenerative disorders, and metabolic syndromes. Investigating the role of TRAP1 provides valuable insights into the mechanisms underlying these conditions, paving the way for the development of novel treatment strategies that target mitochondrial function.
Product Name:
TRAP1 Rabbit Polyclonal Antibody
SKU:
CAB4378
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 445-704 of human TRAP1 (NP_057376.2).
This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. This protein may function in regulating cellular stress responses. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
10131
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TRAP1 Rabbit pAb (CAB4378) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
