The TPBG Polyclonal Antibody (PAC030730) is a valuable tool for researchers studying TPBG, a cell surface glycoprotein involved in tumor progression and metastasis. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the TPBG protein, this antibody allows for the detection and analysis of TPBG expression in various cell types, making it an ideal choice for studies in oncology and cancer research.TPBG, also known as tumor-associated antigen 81 (TACD3), is a promising biomarker for cancer diagnosis and prognosis.
Its overexpression has been linked to aggressive tumor behavior and poor clinical outcomes in various cancer types. Understanding the role of TPBG in tumor growth and metastasis is essential for developing targeted therapies and improving patient outcomes in cancer treatment.Overall, the TPBG Polyclonal Antibody offers researchers a reliable tool for investigating the role of TPBG in cancer progression and metastasis, ultimately leading to a better understanding of the underlying mechanisms and potential therapeutic targets in oncology.
Antibody Name:
Tpbg Antibody (PACO30730)
Antibody SKU:
PACO30730
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA
Recommended Dilutions:
Species Reactivity:
Rat
Immunogen:
Recombinant Rat Trophoblast glycoprotein protein (32-361AA)
Subcellular location: Membrane; Single-pass type I membrane protein Potential. Tissue specificity: Expressed by all types of trophoblasts as early as 9 weeks of development. Specific for trophoblastic cells except for amniotic epithelium. In adult tissues, the expression is limited to a few epithelial cell types but is found on a variety of carcinoma.Miscellaneous: Antigen 5T4 is overexpressed by a wide spectrum of cancers, including colorectal, ovarian and gastric, but with a limited normal tissue expression. Could be used for tumor immunotherapy.Sequence similarities: Contains 6 LRR (leucine-rich) repeats.Contains 1 LRRCT domain.Contains 1 LRRNT domain.
