| UniProt Protein Function: | TMPRSS11D: May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Belongs to the peptidase S1 family. |
| UniProt Protein Details: | Protein type:Protease; EC 3.4.21.-; Membrane protein, integral Chromosomal Location of Human Ortholog: 4q13.2 Cellular Component: extracellular region Molecular Function:peptidase activity Biological Process: proteolysis; respiratory gaseous exchange |
| NCBI Summary: | This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60235 |
| NCBI GenInfo Identifier: | 17376886 |
| NCBI Gene ID: | 9407 |
| NCBI Accession: | O60235.1 |
| UniProt Secondary Accession: | O60235,Q08AF6, |
| UniProt Related Accession: | O60235 |
| Molecular Weight: | 46,263 Da |
| NCBI Full Name: | Transmembrane protease serine 11D |
| NCBI Synonym Full Names: | transmembrane protease, serine 11D |
| NCBI Official Symbol: | TMPRSS11D |
| NCBI Official Synonym Symbols: | HAT |
| NCBI Protein Information: | transmembrane protease serine 11D |
| UniProt Protein Name: | Transmembrane protease serine 11D |
| UniProt Synonym Protein Names: | Airway trypsin-like protease |
| Protein Family: | Transmembrane protease serine |
| UniProt Gene Name: | TMPRSS11D |
| UniProt Entry Name: | TM11D_HUMAN |
