Description
| 抗体名: | TK1 Antibody (PACO43304) |
| 抗体コード: | PACO43304 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human Thymidine kinase, cytosolic protein (1-234AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO43304 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO43304 at dilution of 1:100. |
| バックグラウンド: | TK1(Thymidine kinase, cytosolic) belongs to the thymidine kinase family and is a regulatory enzyme that can interchange between its dimeric and tetrameric forms, which have low and high catalytic efficiencies, respectively. TK1 is involved in DNA synthesis and an important proliferation marker. |
| シノニム: | Thymidine kinase, cytosolic (EC 2.7.1.21), TK1 |
| UniProt Protein Function: | TK: cytosolic thymidine kinase. Phosphorylated during mitosis. Its enzymatic activity is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells. |
| UniProt Protein Details: | Protein type:EC 2.7.1.21; Xenobiotic Metabolism - drug metabolism - other enzymes; Nucleotide Metabolism - pyrimidine; Kinase, other Chromosomal Location of Human Ortholog: 17q23.2-q25.3 Cellular Component: cytosol Molecular Function:identical protein binding; nucleoside kinase activity; zinc ion binding; thymidine kinase activity; ATP binding Biological Process: response to nutrient levels; skeletal muscle cell proliferation; nucleobase, nucleoside and nucleotide metabolic process; response to toxin; liver development; protein homotetramerization; fetal process involved in parturition; deoxyribonucleoside monophosphate biosynthetic process; response to cortisol stimulus; pyrimidine base metabolic process; gut development; response to copper ion; nucleotide biosynthetic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; thymidine metabolic process; pyrimidine nucleoside salvage; phosphorylation |
| UniProt Code: | P04183 |
| NCBI GenInfo Identifier: | 23503074 |
| NCBI Gene ID: | 7083 |
| NCBI Accession: | P04183.2 |
| UniProt Secondary Accession: | P04183,Q969V0, Q9UMG9, B2RC58, |
| UniProt Related Accession: | P04183 |
| Molecular Weight: | 234 |
| NCBI Full Name: | Thymidine kinase, cytosolic |
| NCBI Synonym Full Names: | thymidine kinase 1, soluble |
| NCBI Official Symbol: | TK1 |
| NCBI Official Synonym Symbols: | TK2 |
| NCBI Protein Information: | thymidine kinase, cytosolic; thymidine kinase-1; thymidine kinase 1 soluble isoform |
| UniProt Protein Name: | Thymidine kinase, cytosolic |
| Protein Family: | Thymidine kinase |
| UniProt Gene Name: | TK1 |
| UniProt Entry Name: | KITH_HUMAN |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
