Description
TAGLN3 Antibody (PACO12634)
The TAGLN3 Polyclonal Antibody (PAC012634) is a valuable tool for researchers studying TAGLN3, a protein involved in cell migration and smooth muscle contraction. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the TAGLN3 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell biology and tissue engineering.TAGLN3, also known as transgelin-3, plays a crucial role in regulating the cytoskeleton and cell movement, making it a key player in processes such as wound healing and muscle contraction.
Its involvement in these essential cellular functions makes it a promising target for research in areas like cardiovascular disease, cancer metastasis, and tissue regeneration. Understanding the functions and mechanisms of TAGLN3 can provide valuable insights for developing new therapeutic strategies in these fields.
| Antibody Name: | TAGLN3 Antibody (PACO12634) |
| Antibody SKU: | PACO12634 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human TAGLN3 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.320°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | 199aa,22.4kd; |
| UniProt Protein Function: | TAGLN3: a cytoskeleton-associated protein that colocalizes with microtubules and actin. Its expression rises incrementally during rat brain development, with highest expression during synaptogenesis. Its expression is altered in the frontal cortex but not the motor cortex of alcoholic human brains. Induced in rat brains during adaptation to ethanol. Contains a CH-domain and a Calponin-domain. |
| UniProt Protein Details: | Protein type:Actin-binding Chromosomal Location of Human Ortholog: 3q13.2 Biological Process: central nervous system development |
| UniProt Code: | Q9UI15 |
| NCBI GenInfo Identifier: | 33860182 |
| NCBI Gene ID: | 29114 |
| NCBI Accession: | Q9UI15.2 |
| UniProt Secondary Accession: | Q9UI15,Q96A74, D3DN64, |
| UniProt Related Accession: | Q9UI15 |
| Molecular Weight: | 22,473 Da |
| NCBI Full Name: | Transgelin-3 |
| NCBI Synonym Full Names: | transgelin 3 |
| NCBI Official Symbol: | TAGLN3 |
| NCBI Official Synonym Symbols: | NP22; NP24; NP25 |
| NCBI Protein Information: | transgelin-3 |
| UniProt Protein Name: | Transgelin-3 |
| UniProt Synonym Protein Names: | Neuronal protein 22; NP22; Neuronal protein NP25 |
| Protein Family: | Transgelin |
| UniProt Gene Name: | TAGLN3 |
| UniProt Entry Name: | TAGL3_HUMAN |