Description
| 抗体名: | ST6GAL1 Antibody |
| 抗体コード: | PACO03080 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human CD75. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | ST6GAL1; SIAT1; Beta-galactoside alpha-2; 6-sialyltransferase 1; Alpha 2,6-ST 1; B-cell antigen CD75; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1 |
| UniProt Protein Function: | SIAT1: a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. Is normally found in the trans cisternae of the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found. |
| UniProt Protein Details: | Protein type:EC 2.4.99.1; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 3q27.3 Cellular Component: Golgi membrane Molecular Function:beta-galactoside alpha-2,6-sialyltransferase activity; protein binding; sialyltransferase activity Biological Process: humoral immune response; N-acetylneuraminate metabolic process; O-glycan processing; oligosaccharide metabolic process; protein amino acid N-linked glycosylation via asparagine |
| NCBI Summary: | This gene encodes a member of glycosyltransferase family 29. The encoded protein is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The protein, which is normally found in the Golgi but can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CD75, and CD76. This gene has been incorrectly referred to as CD75. Three transcript variants encoding two different isoforms have been described. [provided by RefSeq, Aug 2009] |
| UniProt Code: | P15907 |
| NCBI GenInfo Identifier: | 115445 |
| NCBI Gene ID: | 6480 |
| NCBI Accession: | P15907.1 |
| UniProt Secondary Accession: | P15907,A8KA14, B2R513, D3DNV3, |
| UniProt Related Accession: | P15907 |
| Molecular Weight: | 47kDa |
| NCBI Full Name: | Beta-galactoside alpha-2,6-sialyltransferase 1 |
| NCBI Synonym Full Names: | ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
| NCBI Official Symbol: | ST6GAL1 |
| NCBI Official Synonym Symbols: | ST6N; SIAT1; ST6GalI |
| NCBI Protein Information: | beta-galactoside alpha-2,6-sialyltransferase 1 |
| UniProt Protein Name: | Beta-galactoside alpha-2,6-sialyltransferase 1 |
| UniProt Synonym Protein Names: | B-cell antigen CD75; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1; ST6Gal I; ST6GalI; Sialyltransferase 1 |
| Protein Family: | Beta-galactoside alpha-2,6-sialyltransferase |
| UniProt Gene Name: | ST6GAL1 |