The SNRNPB Polyclonal Antibody (CAB2009) is a crucial tool for researchers studying SNRNPB, a key component of the spliceosome complex involved in pre-mRNA splicing. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blot applications.SNRNPB, also known as SmB/B', is essential for the formation of spliceosomes, which are molecular machines responsible for accurately removing introns from pre-mRNA. Dysregulation of this process can lead to a variety of diseases, including cancer and genetic disorders.
By targeting SNRNPB with this antibody, researchers can gain valuable insights into the mechanisms of pre-mRNA splicing and its role in disease pathogenesis.With its ability to detect SNRNPB in a variety of cell types, this polyclonal antibody is a valuable tool for studies in molecular biology, genetics, and biochemistry. By understanding the function of SNRNPB, researchers can uncover new therapeutic targets for diseases related to aberrant splicing processes.
Product Name:
SNRPB Rabbit Polyclonal Antibody
SKU:
CAB2009
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SNRPB (NP_003082.1).
The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6628
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SNRPB Rabbit pAb (CAB2009) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
