Description
| 抗体名: | Snaclec rhodocytin subunit α Antibody, FITC conjugated (PACO53940) |
| 抗体コード: | PACO53940 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Calloselasma rhodostoma |
| 免疫原: | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit α protein (1-136AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbα (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. |
| シノニム: | Snaclec rhodocytin subunit α (Aggretin α chain) (Rhodoaggretin subunit alpha) |
| UniProt Protein Function: | Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLC-gamma-2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha-2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9I841 |
| NCBI GenInfo Identifier: | 82174508 |
| NCBI Gene ID: | |
| NCBI Accession: | Q9I841.1 |
| UniProt Secondary Accession: | Q9I841 |
| UniProt Related Accession: | Q9I841 |
| Molecular Weight: | 15,796 Da |
| NCBI Full Name: | Snaclec rhodocytin subunit alpha |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Snaclec rhodocytin subunit alpha |
| UniProt Synonym Protein Names: | Aggretin alpha chain; Rhodoaggretin subunit alpha |
| Protein Family: | Snaclec rhodocytin |
| UniProt Gene Name: | |
| UniProt Entry Name: |
