Description
| 抗体名: | SLU7 Antibody |
| 抗体コード: | PACO02336 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human SLU7. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | SLU7; Pre-mRNA-splicing factor SLU7; hSlu7 |
| UniProt Protein Function: | SLU7: Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. |
| UniProt Protein Details: | Protein type:Spliceosome; RNA splicing; RNA processing Chromosomal Location of Human Ortholog: 5q33.3 Cellular Component: cytoplasm; intracellular membrane-bound organelle; membrane; nuclear speck; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; spliceosome Molecular Function:pre-mRNA 3'-splice site binding; protein binding; second spliceosomal transesterification activity; zinc ion binding Biological Process: alternative nuclear mRNA splicing, via spliceosome; intracellular protein transport; mRNA 3'-end processing; mRNA export from nucleus; nuclear mRNA 3'-splice site recognition; nuclear mRNA splicing, via spliceosome; RNA export from nucleus; RNA splicing, via transesterification reactions; termination of RNA polymerase II transcription |
| NCBI Summary: | Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95391 |
| NCBI GenInfo Identifier: | 262527559 |
| NCBI Gene ID: | 10569 |
| NCBI Accession: | O95391.2 |
| UniProt Secondary Accession: | O95391,Q3LUJ0, Q3LUJ1, Q6RXQ5, Q96FM9, D3DQK2, |
| UniProt Related Accession: | O95391 |
| Molecular Weight: | 68,387 Da |
| NCBI Full Name: | Pre-mRNA-splicing factor SLU7 |
| NCBI Synonym Full Names: | SLU7 homolog, splicing factor |
| NCBI Official Symbol: | SLU7 |
| NCBI Official Synonym Symbols: | 9G8; hSlu7 |
| NCBI Protein Information: | pre-mRNA-splicing factor SLU7 |
| UniProt Protein Name: | Pre-mRNA-splicing factor SLU7 |
| Protein Family: | Pre-mRNA-splicing factor |
| UniProt Gene Name: | SLU7 |
| UniProt Entry Name: | SLU7_HUMAN |
