Description
| 抗体名: | SLC6A8 Antibody |
| 抗体コード: | PACO01507 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the C-terminal region of human SLC6A8. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | SLC6A8; Sodium- and chloride-dependent creatine transporter 1; CT1; Creatine transporter 1; Solute carrier family 6 member 8 |
| UniProt Protein Function: | SLC6A8: Required for the uptake of creatine in muscles and brain. Defects in SLC6A8 are the cause of X-linked creatine deficiency syndrome (XL-CDS). XL-CDS causes developmental delay, hypotonia, mental retardation, seizures, short stature and midface hypoplasia. Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A8 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter, SLC family; Motility/polarity/chemotaxis; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: Xq28 Cellular Component: integral to membrane; integral to plasma membrane; plasma membrane Molecular Function:creatine:sodium symporter activity Biological Process: creatine metabolic process; creatine transport; muscle contraction; transport Disease: Cerebral Creatine Deficiency Syndrome 1 |
| NCBI Summary: | The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008] |
| UniProt Code: | P48029 |
| NCBI GenInfo Identifier: | 1352529 |
| NCBI Gene ID: | 6535 |
| NCBI Accession: | P48029.1 |
| UniProt Secondary Accession: | P48029,Q13032, Q66I36, B2KY47, B4DIA3, E9PFC0, |
| UniProt Related Accession: | P48029 |
| Molecular Weight: | 58,453 Da |
| NCBI Full Name: | Sodium- and chloride-dependent creatine transporter 1 |
| NCBI Synonym Full Names: | solute carrier family 6 member 8 |
| NCBI Official Symbol: | SLC6A8 |
| NCBI Official Synonym Symbols: | CRT; CT1; CRTR; CTR5; CCDS1 |
| NCBI Protein Information: | sodium- and chloride-dependent creatine transporter 1 |
| UniProt Protein Name: | Sodium- and chloride-dependent creatine transporter 1 |
| UniProt Synonym Protein Names: | Solute carrier family 6 member 8 |
| Protein Family: | Sodium- and chloride-dependent creatine transporter |
| UniProt Gene Name: | SLC6A8 |
| UniProt Entry Name: | SC6A8_HUMAN |
