The SLC51B Polyclonal Antibody (PAC047982) is a valuable tool for researchers studying the SLC51B protein, a key player in drug transport and bile acid homeostasis. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, allowing for reliable detection in Western blot applications. By targeting the SLC51B protein, researchers can investigate its function in various cell types and gain valuable insights into its role in drug metabolism and bile acid regulation.SLC51B, also known as the bile acid transporter, plays a crucial role in maintaining bile acid concentrations in the body and facilitating the transport of drugs across cell membranes.
Dysregulation of SLC51B has been linked to various diseases, including cholestasis and drug resistance. Therefore, understanding the mechanisms of SLC51B function is essential for developing targeted therapies and improving treatment outcomes for patients with these conditions.Overall, the SLC51B Polyclonal Antibody offers researchers a reliable tool for studying the function of the SLC51B protein in drug transport and bile acid homeostasis. Its high specificity and sensitivity make it a valuable asset in the fields of pharmacology, hepatology, and drug development.
Antibody Name:
SLC51B Antibody (PACO47982)
Antibody SKU:
PACO47982
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Organic solute transporter subunit β protein (57-128AA)
Immunofluorescent analysis of HepG2 cells using PACO47982 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Essential component of the Ost-alpha/Ost-β complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid, export from enterocytes into portal blood. Efficiently transports the major species of bile acid,. Modulates SLC51A glycosylation, membrane trafficking and stability activities.
Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Modulates SLC51A glycosylation, membrane trafficking and stability activities.
