| UniProt Protein Function: | Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of glutamine and sodium ions with a stoichiometry of 1:1. May also transport small zwitterionic and aliphatic amino acids with a lower affinity. May supply glutamatergic and GABAergic neurons with glutamine which is required for the synthesis of the neurotransmitters glutamate and GABA. |
| UniProt Protein Details: | |
| NCBI Summary: | Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9H2H9 |
| NCBI GenInfo Identifier: | 117168277 |
| NCBI Gene ID: | 81539 |
| NCBI Accession: | NP_001070952.1 |
| UniProt Secondary Accession: | Q9H2H9,Q8NC61, Q8NCF8, Q96JX2, Q9H2Q2 |
| UniProt Related Accession: | Q9H2H9 |
| Molecular Weight: | 54,048 Da |
| NCBI Full Name: | sodium-coupled neutral amino acid transporter 1 isoform 1 |
| NCBI Synonym Full Names: | solute carrier family 38 member 1 |
| NCBI Official Symbol: | SLC38A1 |
| NCBI Official Synonym Symbols: | ATA1; NAT2; SAT1; SNAT1 |
| NCBI Protein Information: | sodium-coupled neutral amino acid transporter 1 |
| UniProt Protein Name: | Sodium-coupled neutral amino acid transporter 1 |
| UniProt Synonym Protein Names: | Amino acid transporter A1; N-system amino acid transporter 2; Solute carrier family 38 member 1; System A amino acid transporter 1; System N amino acid transporter 1 |
| Protein Family: | Serotonin N-acetyltransferase |
| UniProt Gene Name: | SLC38A1 |
| UniProt Entry Name: | |
