Description
| 抗体名: | SLC17A1 Antibody (PACO20539) |
| 抗体コード: | PACO20539 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| 反応性: | Human |
| 免疫原: | Synthetic peptide of human SLC17A1 |
| 憲法: | Liquid |
| ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 精製方法: | Antigen affinity purification |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 60 µg, Lane 1-2: Human kidney cancer tissue, Human kidney pericarcinous tissue, Primary antibody: PACO20539(SLC17A1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
| バックグラウンド: | NPT1, also called sodium-dependent phosphate transport protein, belongs to the organic anion transporter family, SLC17A. It is mainly expressed in the kidney transporting small organic anions such as PAH (para-aminohippurate), but it is also found in the liver and brain. NTP1 localizes to the apical membrane of renal proximal tubular cells and functions as a voltage driven organic anion/Cl-exchanger. It also plays a role in maintaining phosphate homeostasis. The expression of NPT1 is transcriptionally regulated by HNF-1 and HNF-3∫. Indomethacin and salicylate inhibit NPT1-mediated PAH transport. |
| シノニム: | solute carrier family 17 (organic anion transporter), member 1 |
| UniProt Code: | Q14916 |
| NCBI GenInfo Identifier: | 154800443 |
| NCBI Gene ID: | 6568 |
| NCBI Accession: | NP_005065.2 |
| UniProt Related Accession: | Q14916 |
| Molecular Weight: | 22kDa |
| NCBI Full Name: | sodium-dependent phosphate transport protein 1 |
| NCBI Synonym Full Names: | solute carrier family 17 member 1 |
| NCBI Official Symbol: | SLC17A1 |
| NCBI Official Synonym Symbols: | NPT1; NPT-1; NAPI-1 |
| NCBI Protein Information: | sodium-dependent phosphate transport protein 1 |
| UniProt Protein Name: | Sodium-dependent phosphate transport protein 1 |
| UniProt Synonym Protein Names: | Na(+)/PI cotransporter 1; Na/Pi-4; Renal Na(+)-dependent phosphate cotransporter 1; Renal sodium-dependent phosphate transport protein 1; Renal sodium-phosphate transport protein 1; Sodium/phosphate cotransporter 1; Solute carrier family 17 member 1 |
| Protein Family: | Sodium-dependent phosphate transport protein |
| UniProt Gene Name: | SLC17A1 |
| UniProt Entry Name: | NPT1_HUMAN |
