The SHF Antibody (PAC062503) is a polyclonal antibody designed for research involving the SHF protein, a key regulator of cell growth and proliferation. The antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SHF protein, this antibody allows for the detection and analysis of SHF in various cell types, making it an ideal tool for studies in cell biology and cancer research.The SHF protein is known for its role in promoting cell proliferation and survival, making it a potential target for therapeutic interventions in cancer and other diseases characterized by dysregulated cell growth.
By understanding the function of SHF and its implications in cellular processes, researchers can gain valuable insights into potential treatment strategies for various diseases.Overall, the SHF Antibody (PAC062503) is a valuable tool for researchers interested in studying the role of SHF in cell biology and cancer, providing a reliable means of detecting and analyzing SHF protein expression in experimental settings.
Antibody Name:
SHF Antibody (PACO62503)
Antibody SKU:
PACO62503
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human SH2 domain-containing adapter protein F protein (1-159AA)
Immunofluorescence staining of HepG2 cells with PACO62503 at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Background:
Adapter protein which may play a role in the regulation of apoptosis in response to PDGF.
Synonyms:
SH2 domain-containing adapter protein F, SHF
UniProt Protein Function:
SHF: Adapter protein which may play a role in the regulation of apoptosis in response to PDGF. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 15q21.1Biological Process: apoptosis
