Description
| 抗体名: | SH3BP5 Antibody, FITC conjugated (PACO47652) |
| 抗体コード: | PACO47652 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human SH3 domain-binding protein 5 protein (49-455AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. |
| シノニム: | SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK), SH3BP5, SAB |
| UniProt Protein Function: | SH3BP5: Inhibits the auto- and transphosphorylation activity of BTK. Plays a negative regulatory role in BTK-related cytoplasmic signaling in B-cells. May be involved in BCR-induced apoptotic cell death. Belongs to the SH3BP5 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3p24.3Cellular Component: mitochondrion; cytoplasmMolecular Function: protein binding; protein kinase inhibitor activity; SH3 domain bindingBiological Process: negative regulation of protein kinase activity; signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O60239 |
| NCBI GenInfo Identifier: | 124028536 |
| NCBI Gene ID: | 9467 |
| NCBI Accession: | O60239.2 |
| UniProt Secondary Accession: | O60239,Q5JWV9, B3KQW6 |
| UniProt Related Accession: | O60239 |
| Molecular Weight: | 32,202 Da |
| NCBI Full Name: | SH3 domain-binding protein 5 |
| NCBI Synonym Full Names: | SH3-domain binding protein 5 (BTK-associated) |
| NCBI Official Symbol: | SH3BP5 |
| NCBI Official Synonym Symbols: | SAB; SH3BP-5 |
| NCBI Protein Information: | SH3 domain-binding protein 5; SH3 domain-binding protein that preferentially associates with BTK |
| UniProt Protein Name: | SH3 domain-binding protein 5 |
| UniProt Synonym Protein Names: | SH3 domain-binding protein that preferentially associates with BTK |
| Protein Family: | SH3 domain-binding protein |
| UniProt Gene Name: | SH3BP5 |
| UniProt Entry Name: | 3BP5_HUMAN |
