Description
| 抗体名: | SERPINB9 Antibody |
| 抗体コード: | PACO01335 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human PI-9. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | SERPINB9; PI9; Serpin B9; Cytoplasmic antiproteinase 3; CAP-3; CAP3; Peptidase inhibitor 9; PI-9 |
| UniProt Protein Function: | SERPINB9: Granzyme B inhibitor. Belongs to the serpin family. Ov-serpin subfamily. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 6p25 Cellular Component: extracellular space; membrane; cytoplasm; intracellular; nucleus; cytosol Molecular Function:serine-type endopeptidase inhibitor activity; protein binding; protease binding; caspase inhibitor activity Biological Process: mast cell mediated immunity; response to bacterium; immune response; negative regulation of caspase activity; negative regulation by symbiont of host apoptosis; protection from natural killer cell mediated cytotoxicity; negative regulation of apoptosis |
| NCBI Summary: | This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012] |
| UniProt Code: | P50453 |
| NCBI GenInfo Identifier: | 1709896 |
| NCBI Gene ID: | 5272 |
| NCBI Accession: | P50453.1 |
| UniProt Secondary Accession: | P50453,Q5TD03, B2RBW3, |
| UniProt Related Accession: | P50453 |
| Molecular Weight: | 376 |
| NCBI Full Name: | Serpin B9 |
| NCBI Synonym Full Names: | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| NCBI Official Symbol: | SERPINB9 |
| NCBI Official Synonym Symbols: | PI9; CAP3; PI-9; CAP-3 |
| NCBI Protein Information: | serpin B9; peptidase inhibitor 9; cytoplasmic antiproteinase 3; protease inhibitor 9 (ovalbumin type); serpin peptidase inhibitor, clade B, member 9; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 |
| UniProt Protein Name: | Serpin B9 |
| UniProt Synonym Protein Names: | Cytoplasmic antiproteinase 3; CAP-3; CAP3; Peptidase inhibitor 9; PI-9 |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB9 |
| UniProt Entry Name: | SPB9_HUMAN |
