Description
| 抗体名: | SENP2 Antibody |
| 抗体コード: | PACO03060 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the C-terminal region of human SENP2. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | SENP2; KIAA1331; Sentrin-specific protease 2; Axam2; SMT3-specific isopeptidase 2; Smt3ip2; Sentrin/SUMO-specific protease SENP2 |
| UniProt Protein Function: | SENP2: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. Belongs to the peptidase C48 family. |
| UniProt Protein Details: | Protein type:Protease; EC 3.4.22.68 Chromosomal Location of Human Ortholog: 3q27.2 Cellular Component: nuclear pore; nucleoplasm; PML body Molecular Function:endopeptidase activity; protein binding; SUMO-specific protease activity Biological Process: fat cell differentiation; negative regulation of protein ubiquitination; positive regulation of protein ubiquitination; protein destabilization; protein desumoylation; protein sumoylation |
| NCBI Summary: | SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9HC62 |
| NCBI GenInfo Identifier: | 143811458 |
| NCBI Gene ID: | 59343 |
| NCBI Accession: | Q9HC62.3 |
| UniProt Secondary Accession: | Q9HC62,Q8IW97, Q96SR2, Q9P2L5, B4DQ42, |
| UniProt Related Accession: | Q9HC62 |
| Molecular Weight: | 66,358 Da |
| NCBI Full Name: | Sentrin-specific protease 2 |
| NCBI Synonym Full Names: | SUMO1/sentrin/SMT3 specific peptidase 2 |
| NCBI Official Symbol: | SENP2 |
| NCBI Official Synonym Symbols: | AXAM2; SMT3IP2 |
| NCBI Protein Information: | sentrin-specific protease 2 |
| UniProt Protein Name: | Sentrin-specific protease 2 |
| UniProt Synonym Protein Names: | Axam2; SMT3-specific isopeptidase 2; Smt3ip2; Sentrin/SUMO-specific protease SENP2 |
| Protein Family: | Sentrin-specific protease |
| UniProt Gene Name: | SENP2 |
| UniProt Entry Name: | SENP2_HUMAN |
