Description
| 抗体名: | SEC23IP Antibody, FITC conjugated (PACO51244) |
| 抗体コード: | PACO51244 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human SEC23-interacting protein (779-989AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P). |
| シノニム: | SEC23-interacting protein (p125), SEC23IP |
| UniProt Protein Function: | SEC23IP: Plays a role in the organization of endoplasmic reticulum exit sites. Belongs to the PA-PLA1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Endoplasmic reticulum Chromosomal Location of Human Ortholog: 10q25-q26 Cellular Component: cis-Golgi network; intracellular membrane-bound organelle; cytoplasm; ER-Golgi intermediate compartment Molecular Function:metal ion binding Biological Process: acrosome formation; intracellular protein transport; single fertilization; Golgi organization and biogenesis |
| NCBI Summary: | This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011] |
| UniProt Code: | Q9Y6Y8 |
| NCBI GenInfo Identifier: | 55584014 |
| NCBI Gene ID: | 11196 |
| NCBI Accession: | Q9Y6Y8.1 |
| UniProt Related Accession: | Q9Y6Y8 |
| Molecular Weight: | 102kDa; 111kDa |
| NCBI Full Name: | SEC23-interacting protein |
| NCBI Synonym Full Names: | SEC23 interacting protein |
| NCBI Official Symbol: | SEC23IP |
| NCBI Official Synonym Symbols: | P125; P125A; MSTP053 |
| NCBI Protein Information: | SEC23-interacting protein |
| UniProt Protein Name: | SEC23-interacting protein |
| UniProt Synonym Protein Names: | p125 |
| Protein Family: | SEC23-interacting protein |
| UniProt Gene Name: | SEC23IP |
| UniProt Entry Name: | S23IP_HUMAN |
