Description
| 抗体名: | RNF125 Antibody (PACO11865) |
| 抗体コード: | PACO11865 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human RNF125 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | ring finger protein 125;RNF125;FLJ20456;MGC21737;TRAC1 ; |
| UniProt Protein Function: | RNF125: E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. |
| UniProt Protein Details: | Protein type:Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.19; EC 6.3.2.-; Ligase Chromosomal Location of Human Ortholog: 18q12.1 Molecular Function:zinc ion binding; ubiquitin-protein ligase activity; ligase activity Biological Process: protein ubiquitination; innate immune response; negative regulation of interferon type I production Disease: Tenorio Syndrome |
| NCBI Summary: | This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012] |
| UniProt Code: | Q96EQ8 |
| NCBI GenInfo Identifier: | 37595555 |
| NCBI Gene ID: | 54941 |
| NCBI Accession: | NP_060301 |
| UniProt Related Accession: | Q96EQ8 |
| Molecular Weight: | 26kDa |
| NCBI Full Name: | E3 ubiquitin-protein ligase RNF125 |
| NCBI Synonym Full Names: | ring finger protein 125 |
| NCBI Official Symbol: | RNF125 |
| NCBI Official Synonym Symbols: | TNORS; TRAC1; TRAC-1 |
| NCBI Protein Information: | E3 ubiquitin-protein ligase RNF125 |
| UniProt Protein Name: | E3 ubiquitin-protein ligase RNF125 |
| UniProt Synonym Protein Names: | RING finger protein 125; T-cell RING activation protein 1 |
| Protein Family: | E3 ubiquitin-protein ligase |
| UniProt Gene Name: | RNF125 |
| UniProt Entry Name: | RN125_HUMAN |
