Description
| Product Name: | Recombinant Mouse Alpha-1-antitrypsin 1-1/Serpin A1e (C-6His) |
| Product Code: | RPES6628 |
| Size: | 10µg |
| Species: | Mouse |
| Expression Host: | HEK293 Cells |
| Synonyms: | Alpha-1-antitrypsin 1-5, Alpha-1 protease inhibitor 5, Serine protease inhibitor 1-5, Serine protease inhibitor A1e, Serpin A1e, Serpina1e, Dom5, Spi1-5 |
| Mol Mass: | 44.5 kDa |
| AP Mol Mass: | 47-60 kDa |
| Tag: | C-6His |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Bio Activity: | Testing in progress |
| Sequence: | Glu25-Lys413 |
| Accession: | Q00898 |
| Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation: | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed ma |
| Reconstitution: | Not Applicable |
| Background: | Alpha-1-antitrypsin 1-5(SERPIN A1) is a secreted protein and belongs to the serpin family. Serpins bind the protease active site resulting in a major conformational rearrangement that traps the enzyme in a covalent acyl-enzyme intermediate. Mouse SERPIN A1 is a serine protease inhibitor whose targets include elastase,plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema orliver disease. Several transcript variants encoding the same protein have been found for this gene. |
