Description
| Product Name: | Recombinant human Flt-3 Ligand Protein (His Tag) |
| SKU: | RPES8370 |
| Size: | 20μg |
| Tag: | C-His |
| Reactivity: | human |
| Expression Host: | Mammalian |
| Accession: | P49771 |
| Sequence: | Thr27-Pro184 |
| Calculated Molecular Weight: | 17.3 kDa |
| Observed Molecular Weight: | 25-35 kDa |
| Synonyms: | FL, Flt3 Ligand, Flt3-L, Fms-Felated Tyrosine Kinase 3 Ligand, Fms-Related Tyrosine Kinase 3 ligand, SL Cytokine, FLT3LG, Flt3L |
| Endotoxin: | < 1.0 EU/mg of the protein as determined by the LAL method |
| Purity: | > 90% as determined by reducing SDS-PAGE. |
FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
| Bio-activity: | Not validated for activity |
| Formulation: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Reconstitution: | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis. |
| Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
