The RBM14 Polyclonal Antibody (CAB4418) is a vital tool for researchers studying RNA-binding motif protein 14 (RBM14), a key player in RNA metabolism and gene expression regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity in detecting RBM14 in human samples, making it a valuable asset for experiments involving Western blot analyses.RBM14 is known to interact with various RNA molecules, influencing processes like splicing and mRNA stability. Its dysregulation has been implicated in diseases such as cancer, making it a prime target for further investigation.
By targeting RBM14 with this polyclonal antibody, researchers can gain valuable insights into its function and its role in disease progression, offering potential avenues for new therapeutic interventions.With its ability to pinpoint RBM14 in different cell types, this antibody is indispensable for studies in molecular biology, oncology, and beyond. By utilizing the RBM14 Polyclonal Antibody, researchers can deepen their understanding of RNA metabolism and potentially uncover novel strategies for combating diseases associated with RBM14 dysregulation.
Product Name:
RBM14 Rabbit Polyclonal Antibody
SKU:
CAB4418
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-220 of human RBM14 (NP_006319.1).
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
10432
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RBM14 antibody (CAB4418) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
