Description
| 抗体名: | PTP4A1 Antibody (PACO39254) |
| 抗体コード: | PACO39254 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Protein tyrosine phosphatase type IVA 1 protein (1-170AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| バックグラウンド: | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. |
| シノニム: | Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1), PTP4A1, PRL1 PTPCAAX1 |
| UniProt Protein Function: | PTP4A1: Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. Belongs to the protein-tyrosine phosphatase family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 3.1.3.48; Protein phosphatase, tyrosine (non-receptor) Chromosomal Location of Human Ortholog: 6q12 Cellular Component: cytoplasm; internal side of plasma membrane; nucleus Molecular Function:protein tyrosine phosphatase activity Biological Process: positive regulation of cell migration |
| NCBI Summary: | This gene encodes a member of a small class of prenylated protein tyrosine phosphatases (PTPs), which contain a PTP domain and a characteristic C-terminal prenylation motif. The encoded protein is a cell signaling molecule that plays regulatory roles in a variety of cellular processes, including cell proliferation and migration. The protein may also be involved in cancer development and metastasis. This tyrosine phosphatase is a nuclear protein, but may associate with plasma membrane by means of its prenylation motif. Pseudogenes related to this gene are located on chromosomes 1, 2, 5, 7, 11 and X. [provided by RefSeq, Jun 2013] |
| UniProt Code: | Q93096 |
| NCBI GenInfo Identifier: | 68566217 |
| NCBI Gene ID: | 7803 |
| NCBI Accession: | Q93096.2 |
| UniProt Secondary Accession: | Q93096,O00648, Q49A54, B2R6C8, |
| UniProt Related Accession: | Q93096 |
| Molecular Weight: | 19,815 Da |
| NCBI Full Name: | Protein tyrosine phosphatase type IVA 1 |
| NCBI Synonym Full Names: | protein tyrosine phosphatase type IVA, member 1 |
| NCBI Official Symbol: | PTP4A1 |
| NCBI Official Synonym Symbols: | HH72; PRL1; PRL-1; PTPCAAX1; PTP(CAAX1) |
| NCBI Protein Information: | protein tyrosine phosphatase type IVA 1 |
| UniProt Protein Name: | Protein tyrosine phosphatase type IVA 1 |
| UniProt Synonym Protein Names: | PTP(CAAXI); Protein-tyrosine phosphatase 4a1; Protein-tyrosine phosphatase of regenerating liver 1; PRL-1 |
| Protein Family: | Protein tyrosine phosphatase |
| UniProt Gene Name: | PTP4A1 |
| UniProt Entry Name: | TP4A1_HUMAN |
