Description
| 抗体名: | PSMD6 Antibody (PACO05830) |
| 抗体コード: | PACO05830 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Synthesized peptide derived from the Internal region of human p44S10. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | PSMD6; KIAA0107; PFAAP4; 26S proteasome non-ATPase regulatory subunit 6; 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4; |
| UniProt Protein Function: | PSMD6: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Belongs to the proteasome subunit S10 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 3p14.1 Cellular Component: nucleoplasm; proteasome complex; proteasome regulatory particle; cytosol Molecular Function:ATPase activity Biological Process: positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle; proteasomal ubiquitin-dependent protein catabolic process; negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle; protein polyubiquitination; viral reproduction; apoptosis; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; proteolysis; DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; regulation of apoptosis; antigen processing and presentation of peptide antigen via MHC class I; regulation of ubiquitin-protein ligase activity during mitotic cell cycle; anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of exogenous peptide antigen via MHC class I; gene expression; mitotic cell cycle; regulation of amino acid metabolic process; negative regulation of apoptosis; G1/S transition of mitotic cell cycle |
| NCBI Summary: | This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012] |
| UniProt Code: | Q15008 |
| NCBI GenInfo Identifier: | 7661914 |
| NCBI Gene ID: | 9861 |
| NCBI Accession: | NP_055629.1 |
| UniProt Secondary Accession: | Q15008,Q6UV22, A8K2E0, E9PHI9, |
| UniProt Related Accession: | Q15008 |
| Molecular Weight: | 51,923 Da |
| NCBI Full Name: | 26S proteasome non-ATPase regulatory subunit 6 isoform 2 |
| NCBI Synonym Full Names: | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 |
| NCBI Official Symbol: | PSMD6 |
| NCBI Official Synonym Symbols: | S10; Rpn7; p42A; p44S10; SGA-113M |
| NCBI Protein Information: | 26S proteasome non-ATPase regulatory subunit 6; breast cancer-associated protein SGA-113M; phosphonoformate immuno-associated protein 4; proteasome regulatory particle subunit p44S10 |
| UniProt Protein Name: | 26S proteasome non-ATPase regulatory subunit 6 |
| UniProt Synonym Protein Names: | 26S proteasome regulatory subunit RPN7; 26S proteasome regulatory subunit S10; Breast cancer-associated protein SGA-113M; Phosphonoformate immuno-associated protein 4; Proteasome regulatory particle subunit p44S10; p42A |
| UniProt Gene Name: | PSMD6 |
| UniProt Entry Name: | PSMD6_HUMAN |
