Description
| 抗体名: | PRSS12 Antibody, Biotin conjugated (PACO46145) |
| 抗体コード: | PACO46145 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Neurotrypsin protein (631-874AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. |
| シノニム: | Neurotrypsin (EC 3.4.21) (Leydin) (Motopsin) (Serine protease 12), PRSS12 |
| UniProt Protein Function: | PRSS12: Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Defects in PRSS12 are the cause of mental retardation autosomal recessive type 1 (MRT1). Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. Belongs to the peptidase S1 family. |
| UniProt Protein Details: | Protein type:Vesicle; Secreted, signal peptide; EC 3.4.21.-; Secreted; Protease Chromosomal Location of Human Ortholog: 4q28.1 Cellular Component: axon; plasma membrane Molecular Function:serine-type peptidase activity Biological Process: exocytosis Disease: Mental Retardation, Autosomal Recessive 1 |
| NCBI Summary: | This gene encodes a member of the trypsin family of serine proteases. Studies in mouse suggest that the encoded enzyme may be involved in structural reorganizations associated with learning and memory. The enzyme is also expressed in Leydig cells in the testis, but its function in this tissue is unknown. Defects in this gene are a cause of mental retardation autosomal recessive type 1 (MRT1). [provided by RefSeq, Jul 2010] |
| UniProt Code: | P56730 |
| NCBI GenInfo Identifier: | 259016287 |
| NCBI Gene ID: | 8492 |
| NCBI Accession: | P56730.2 |
| UniProt Secondary Accession: | P56730,Q9UP16, |
| UniProt Related Accession: | P56730 |
| Molecular Weight: | 97,067 Da |
| NCBI Full Name: | Neurotrypsin |
| NCBI Synonym Full Names: | protease, serine 12 |
| NCBI Official Symbol: | PRSS12 |
| NCBI Official Synonym Symbols: | MRT1; BSSP3; BSSP-3 |
| NCBI Protein Information: | neurotrypsin |
| UniProt Protein Name: | Neurotrypsin |
| UniProt Synonym Protein Names: | Leydin; Motopsin; Serine protease 12 |
| Protein Family: | Neurotrypsin |
| UniProt Gene Name: | PRSS12 |
| UniProt Entry Name: | NETR_HUMAN |
