| UniProt Protein Function: | Binds activated protein C. Enhances protein C activation by the thrombin-thrombomodulin complex; plays a role in the protein C pathway controlling blood coagulation. |
| NCBI Summary: | The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9UNN8 |
| NCBI GenInfo Identifier: | 13626550 |
| NCBI Gene ID: | 10544 |
| NCBI Accession: | Q9UNN8.1 |
| UniProt Secondary Accession: | Q9UNN8,Q14218, Q6IB56, Q96CB3, Q9ULX1, B2RC04, |
| UniProt Related Accession: | Q9UNN8 |
| Molecular Weight: | 26,671 Da |
| NCBI Full Name: | Endothelial protein C receptor |
| NCBI Synonym Full Names: | protein C receptor |
| NCBI Official Symbol: | PROCR |
| NCBI Official Synonym Symbols: | CCCA; EPCR; CCD41 |
| NCBI Protein Information: | endothelial protein C receptor |
| UniProt Protein Name: | Endothelial protein C receptor |
| UniProt Synonym Protein Names: | Activated protein C receptor; APC receptor; Endothelial cell protein C receptor; CD_antigen: CD201 |
| Protein Family: | Endothelial protein C receptor |
| UniProt Gene Name: | PROCR |
