Description
| 抗体名: | PPP2CB Antibody, HRP conjugated (PACO27174) |
| 抗体コード: | PACO27174 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Serine/threonine-protein phosphatase 2A catalytic subunit β isoform protein (1-309AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | HRP |
| バックグラウンド: | PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. |
| シノニム: | Serine/threonine-protein phosphatase 2A catalytic subunit β isoform (PP2A-beta) (EC 3.1.3.16), PPP2CB |
| UniProt Protein Function: | PPP2CB: one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. |
| UniProt Protein Details: | Protein type:Protein phosphatase, Ser/Thr (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.16 Chromosomal Location of Human Ortholog: 8p12 Cellular Component: spindle pole; protein phosphatase type 2A complex; nucleus; cytosol; chromosome, pericentric region Molecular Function:protein C-terminus binding; protein binding; metal ion binding; protein serine/threonine phosphatase activity Biological Process: response to antibiotic; proteasomal ubiquitin-dependent protein catabolic process; apoptotic mitochondrial changes; fibroblast growth factor receptor signaling pathway; response to hydrogen peroxide; regulation of gene expression; negative regulation of Ras protein signal transduction; protein amino acid dephosphorylation |
| NCBI Summary: | This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010] |
| UniProt Code: | P62714 |
| NCBI GenInfo Identifier: | 50402236 |
| NCBI Gene ID: | 5516 |
| NCBI Accession: | P62714.1 |
| UniProt Secondary Accession: | P62714,P67775, P62715, P63330, P62716 P63331, |
| UniProt Related Accession: | P62714 |
| Molecular Weight: | 35kDa |
| NCBI Full Name: | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| NCBI Synonym Full Names: | protein phosphatase 2 catalytic subunit beta |
| NCBI Official Symbol: | PPP2CB |
| NCBI Official Synonym Symbols: | PP2CB; PP2Abeta |
| NCBI Protein Information: | serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| UniProt Protein Name: | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform |
| Protein Family: | PP2A regulatory |
| UniProt Gene Name: | PPP2CB |
| UniProt Entry Name: | PP2AB_HUMAN |
