Description
| 抗体名: | PPM1K Antibody (PACO38242) |
| 抗体コード: | PACO38242 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| 反応性: | Human, Mouse |
| 免疫原: | Recombinant Human Protein phosphatase 1K, mitochondrial protein (30-372AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: A549 whole cell lysate, Mouse skeletal muscle tissue. All lanes: PPM1K antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 41, 26, 17 kDa. Observed band size: 41 kDa. |
 | Immunohistochemistry of paraffin-embedded human colon cancer using PACO38242 at dilution of 1:100. |
| バックグラウンド: | Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development. |
| シノニム: | Protein phosphatase 1K, mitochondrial (EC 3.1.3.16) (PP2C domain-containing protein phosphatase 1K) (PP2C-like mitochondrial protein) (PP2C-type mitochondrial phosphoprotein phosphatase) (PTMP) (Protein phosphatase 2C isoform kappa) (PP2C-kappa), PPM1K, PP2CM |
| UniProt Protein Function: | PPM1K: Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development. Belongs to the PP2C family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Mitochondrial; Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 4q22.1 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:metal ion binding; protein binding; protein serine/threonine phosphatase activity Biological Process: branched chain family amino acid catabolic process; protein amino acid dephosphorylation Disease: Maple Syrup Urine Disease, Mild Variant |
| NCBI Summary: | This gene encodes a member of the PPM family of Mn2+/Mg2+-dependent protein phosphatases. The encoded protein, essential for cell survival and development, is targeted to the mitochondria where it plays a key role in regulation of the mitochondrial permeability transition pore. [provided by RefSeq, Sep 2012] |
| UniProt Code: | Q8N3J5 |
| NCBI GenInfo Identifier: | 74750962 |
| NCBI Gene ID: | 152926 |
| NCBI Accession: | Q8N3J5.1 |
| UniProt Secondary Accession: | Q8N3J5,Q05CT5, Q49AB5, Q4W5E6, Q56AN8, Q8IUZ7, Q8IXG7 Q8ND70, Q96NT4, B2RAZ1, |
| UniProt Related Accession: | Q8N3J5 |
| Molecular Weight: | 16,759 Da |
| NCBI Full Name: | Protein phosphatase 1K, mitochondrial |
| NCBI Synonym Full Names: | protein phosphatase, Mg2+/Mn2+ dependent 1K |
| NCBI Official Symbol: | PPM1K |
| NCBI Official Synonym Symbols: | BDP; PTMP; PP2Cm; MSUDMV; PP2Ckappa; UG0882E07 |
| NCBI Protein Information: | protein phosphatase 1K, mitochondrial |
| UniProt Protein Name: | Protein phosphatase 1K, mitochondrial |
| UniProt Synonym Protein Names: | PP2C domain-containing protein phosphatase 1K; PP2C-like mitochondrial protein; PP2C-type mitochondrial phosphoprotein phosphatase; PTMP; Protein phosphatase 2C isoform kappa; PP2C-kappa |
| Protein Family: | Protein phosphatase |
| UniProt Gene Name: | PPM1K |
| UniProt Entry Name: | PPM1K_HUMAN |
