Description
| 抗体名: | POLA2 Antibody (PACO11340) |
| 抗体コード: | PACO11340 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Human POLA2 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | polymerase (DNA directed), α 2 (70kD subunit);POLA2;FLJ21662;FLJ37250 ; |
| UniProt Protein Function: | POLA2: a DNA polymerase that may play an essential role at the early stage of chromosomal DNA replication by coupling the polymerase alpha/primase complex to the cellular replication machinery. DNA polymerase alpha-primase is a four subunit enzyme (subunits A, B, C and D), which is assembled throughout the cell cycle. The largest subunit (subunit A) has DNA polymerase activity, the two smallest subunits (subunits C and D) have DNA primase activity. Subunit B binds to subunit A. Phosphorylated in a cell cycle-dependent manner, in G2/M phase. |
| UniProt Protein Details: | Protein type:Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; DNA replication Chromosomal Location of Human Ortholog: 11q13.1 Cellular Component: nucleoplasm; alpha DNA polymerase:primase complex; cytoplasm Molecular Function:DNA binding; protein heterodimerization activity; DNA-directed DNA polymerase activity Biological Process: telomere maintenance via semi-conservative replication; DNA replication initiation; protein import into nucleus, translocation; telomere maintenance via recombination; mitotic cell cycle; DNA strand elongation during DNA replication; DNA replication; telomere maintenance; G1/S transition of mitotic cell cycle |
| UniProt Code: | Q14181 |
| NCBI GenInfo Identifier: | 90110415 |
| NCBI Gene ID: | 23649 |
| NCBI Accession: | Q14181.2 |
| UniProt Secondary Accession: | Q14181,Q9BPV3, B4DNB4, |
| UniProt Related Accession: | Q14181 |
| Molecular Weight: | 598 |
| NCBI Full Name: | DNA polymerase alpha subunit B |
| NCBI Synonym Full Names: | polymerase (DNA directed), alpha 2, accessory subunit |
| NCBI Official Symbol: | POLA2 |
| NCBI Protein Information: | DNA polymerase alpha subunit B; DNA polymerase alpha 70 kDa subunit; polymerase (DNA-directed), alpha (70kD); polymerase (DNA directed), alpha 2 (70kD subunit) |
| UniProt Protein Name: | DNA polymerase alpha subunit B |
| UniProt Synonym Protein Names: | DNA polymerase alpha 70 kDa subunit |
| Protein Family: | DNA polymerase |
| UniProt Gene Name: | POLA2 |
| UniProt Entry Name: | DPOA2_HUMAN |
