Description
| 抗体名: | PNMT Antibody (PACO11330) |
| 抗体コード: | PACO11330 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human PNMT |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | phenylethanolamine N-methyltransferase;PNMT;MGC34570;PENT;PNMTase ; |
| UniProt Protein Function: | PNMT: Converts noradrenaline to adrenaline. Belongs to the NNMT/PNMT/TEMT family. |
| UniProt Protein Details: | Protein type:Methyltransferase; EC 2.1.1.28; Amino Acid Metabolism - tyrosine Chromosomal Location of Human Ortholog: 17q12 Cellular Component: cytosol Molecular Function:phenylethanolamine N-methyltransferase activity Biological Process: methylation; catecholamine biosynthetic process; epinephrine biosynthetic process Disease: Hypertension, Essential |
| NCBI Summary: | The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012] |
| UniProt Code: | P11086 |
| NCBI GenInfo Identifier: | 130375 |
| NCBI Gene ID: | 5409 |
| NCBI Accession: | P11086.1 |
| UniProt Related Accession: | P11086 |
| Molecular Weight: | 282 |
| NCBI Full Name: | Phenylethanolamine N-methyltransferase |
| NCBI Synonym Full Names: | phenylethanolamine N-methyltransferase |
| NCBI Official Symbol: | PNMT |
| NCBI Official Synonym Symbols: | PENT; PNMTase |
| NCBI Protein Information: | phenylethanolamine N-methyltransferase; phenylethanolamine N-methylase; noradrenaline N-methyltransferase |
| UniProt Protein Name: | Phenylethanolamine N-methyltransferase |
| UniProt Synonym Protein Names: | Noradrenaline N-methyltransferase |
| Protein Family: | Phenylethanolamine N-methyltransferase |
| UniProt Gene Name: | PNMT |
| UniProt Entry Name: | PNMT_HUMAN |