Description
| 抗体名: | PLIN5 Antibody, Biotin conjugated (PACO46757) |
| 抗体コード: | PACO46757 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Recombinant Human Perilipin-5 protein (305-453AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Biotin |
| バックグラウンド: | Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid, oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acid, in the form of triglycerides and the release of fatty acid, for mitochondrial fatty acid, oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity). |
| シノニム: | Perilipin-5 (Lipid storage droplet protein 5), PLIN5, LSDP5 OXPAT PAT-1 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q00G26 |
| NCBI GenInfo Identifier: | 363901035 |
| NCBI Gene ID: | |
| NCBI Accession: | AEW43286.1 |
| UniProt Secondary Accession: | Q00G26 |
| UniProt Related Accession: | Q00G26 |
| Molecular Weight: | |
| NCBI Full Name: | major lipid droplet protein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | |
| UniProt Synonym Protein Names: | |
| Protein Family: | |
| UniProt Gene Name: | |
| UniProt Entry Name: |
