Description
| 抗体名: | PLA2G4C Antibody (PACO44845) |
| 抗体コード: | PACO44845 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| 反応性: | Human, Mouse |
| 免疫原: | Recombinant Human Cytosolic phospholipase A2 γ protein (1-189AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: COX10 antibody at 5.84µg/ml + Mouse heart tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 61, 60, 63 kDa. Observed band size: 61 kDa.. |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO44845 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO44845 at dilution of 1:100. |
| バックグラウンド: | Has a preference for arachidonic acid, at the sn-2 position of phosphatidylcholine as compared with palmitic acid, |
| シノニム: | Cytosolic phospholipase A2 γ (cPLA2-gamma) (EC 3.1.1.4) (Phospholipase A2 group IVC), PLA2G4C |
| UniProt Protein Function: | PLA2G4C: a calcium-independent phospholipase A2 that catalyzes the release of arachidonic acid from membrane phospholipids. Has a preference for arachidonic acid at the sn-2 position of phosphatidylcholine as compared with palmitic acid. Highly expressed in heart and skeletal muscle. |
| UniProt Protein Details: | Protein type:Phospholipase; Lipid Metabolism - arachidonic acid; EC 3.1.1.4 Chromosomal Location of Human Ortholog: 19q13.3 Cellular Component: nucleoplasm; endoplasmic reticulum membrane; membrane; nuclear envelope; cell cortex; cytosol Molecular Function:calcium-independent phospholipase A2 activity; phospholipid binding Biological Process: glycerophospholipid catabolic process; phospholipid metabolic process; glycerophospholipid biosynthetic process; arachidonic acid metabolic process; parturition; inflammatory response |
| NCBI Summary: | This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009] |
| UniProt Code: | Q9UP65 |
| NCBI GenInfo Identifier: | 226693357 |
| NCBI Gene ID: | 8605 |
| NCBI Accession: | NP_001152794.1 |
| UniProt Secondary Accession: | Q9UP65,O75457, Q6IBI8, Q9UG68, B2RB71, B4DI40, |
| UniProt Related Accession: | Q9UP65 |
| Molecular Weight: | 62,451 Da |
| NCBI Full Name: | cytosolic phospholipase A2 gamma isoform 2 |
| NCBI Synonym Full Names: | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| NCBI Official Symbol: | PLA2G4C |
| NCBI Official Synonym Symbols: | CPLA2-gamma |
| NCBI Protein Information: | cytosolic phospholipase A2 gamma; phospholipase A2 group IVC |
| UniProt Protein Name: | Cytosolic phospholipase A2 gamma |
| UniProt Synonym Protein Names: | Phospholipase A2 group IVC |
| Protein Family: | Cytosolic phospholipase |
| UniProt Gene Name: | PLA2G4C |
| UniProt Entry Name: | PA24C_HUMAN |
