Description
| 抗体名: | PIP5K1B Antibody (PACO44786) |
| 抗体コード: | PACO44786 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| 反応性: | Human, Mouse |
| 免疫原: | Recombinant Human Phosphatidylinositol 4-phosphate 5-kinase type-1 β protein (190-470AA) |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: PIP5K1B antibody at 5.46µg/ml. Lane 1: Human placenta tissue. Lane 2: Mouse kidney tissue. Lane 3: Mouse skeletal muscle tissue. Lane 4: Mouse heart tissue. Lane 5: Mouse brain tissue. Lane 6: Mouse lung tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 62, 63, 57 kDa. Observed band size: 62 kDa.. |
 | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO44786 at dilution of 1:100. |
| バックグラウンド: | Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion (By similarity). |
| シノニム: | Phosphatidylinositol 4-phosphate 5-kinase type-1 β (PIP5K1-beta) (PtdIns(4)P-5-kinase 1 beta) (EC 2.7.1.68) (Phosphatidylinositol 4-phosphate 5-kinase type I beta) (PIP5KIbeta) (Protein STM-7) (Type I phosphatidylinositol 4-phosphate 5-kinase beta), PIP5K1B, STM7 |
| UniProt Protein Function: | PIP5K1B: Participates in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of PLD2. Together with PIP5K1A is required after stimulation of G-protein coupled receptors for stable platelet adhesion. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.68; Kinase, lipid Chromosomal Location of Human Ortholog: 9q13 Cellular Component: membrane; endomembrane system; uropod; cytosol Molecular Function:protein binding; 1-phosphatidylinositol-4-phosphate 5-kinase activity; ATP binding Biological Process: phosphoinositide phosphorylation; phospholipid metabolic process; phosphatidylinositol biosynthetic process |
| UniProt Code: | O14986 |
| NCBI GenInfo Identifier: | 78099085 |
| NCBI Gene ID: | 8395 |
| NCBI Accession: | O14986.2 |
| UniProt Secondary Accession: | O14986,P78518, P78519, Q5T5K6, Q5T5K8, Q5T5K9, Q5VZ00 Q7KYT5, Q8NHQ5, Q92749, A8K9L9, B4DIG7, |
| UniProt Related Accession: | O14986 |
| Molecular Weight: | 540 |
| NCBI Full Name: | Phosphatidylinositol 4-phosphate 5-kinase type-1 beta |
| NCBI Synonym Full Names: | phosphatidylinositol-4-phosphate 5-kinase, type I, beta |
| NCBI Official Symbol: | PIP5K1B |
| NCBI Official Synonym Symbols: | MSS4; STM7 |
| NCBI Protein Information: | phosphatidylinositol 4-phosphate 5-kinase type-1 beta; PIP5KIbeta; PIP5K1-beta; protein STM-7; ptdIns(4)P-5-kinase 1 beta; phosphatidylinositol 4-phosphate 5-kinase type I beta; phosphatidylinositol-4-phosphate 5-kinase type-1 beta; type I phosphatidylinositol 4-phosphate 5-kinase beta; type I phosphatidylinositol-4-phosphate 5-kinase beta |
| UniProt Protein Name: | Phosphatidylinositol 4-phosphate 5-kinase type-1 beta |
| UniProt Synonym Protein Names: | Phosphatidylinositol 4-phosphate 5-kinase type I beta; PIP5KIbeta; Protein STM-7; Type I phosphatidylinositol 4-phosphate 5-kinase beta |
| Protein Family: | Phosphatidylinositol 4-phosphate 5-kinase |
| UniProt Gene Name: | PIP5K1B |
| UniProt Entry Name: | PI51B_HUMAN |
