Description
| 抗体名: | PINX1 Antibody |
| 抗体コード: | PACO04667 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, IHC |
| 推奨される希釈: | IHC:1:100-1:300 |
| 反応性: | Human |
| 免疫原: | synthesized peptide derived from the Internal region of human PinX1. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | PINX1; LPTL; LPTS; PIN2/TERF1-interacting telomerase inhibitor 1; Liver-related putative tumor suppressor; Pin2-interacting protein X1; Protein 67-11-3; TRF1-interacting protein 1 |
| UniProt Protein Function: | PINX1: Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor. Belongs to the PINX1 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Nucleolus; Tumor suppressor; Inhibitor Chromosomal Location of Human Ortholog: 8p23 Cellular Component: cytoplasm; intracellular membrane-bound organelle; kinetochore; mitochondrion; nuclear chromosome; nuclear chromosome, telomeric region; nucleolus; nucleus; spindle Molecular Function:protein binding Biological Process: mitotic metaphase plate congression; negative regulation of cell proliferation; negative regulation of protein ubiquitination; negative regulation of telomerase activity; negative regulation of telomere maintenance via telomerase; regulation of protein stability; regulation of telomerase activity; telomere maintenance via telomerase |
| UniProt Code: | Q96BK5 |
| NCBI GenInfo Identifier: | 547234890 |
| NCBI Gene ID: | 54984 |
| NCBI Accession: | NP_001271285.1 |
| UniProt Secondary Accession: | Q96BK5,Q548A5, Q6QWG9, Q7Z7J8, Q96QD7, Q9HBU7, Q9NWW2 B2R9B1, |
| UniProt Related Accession: | Q96BK5 |
| Molecular Weight: | 19,714 Da |
| NCBI Full Name: | PIN2/TERF1-interacting telomerase inhibitor 1 isoform 2 |
| NCBI Synonym Full Names: | PIN2/TERF1 interacting, telomerase inhibitor 1 |
| NCBI Official Symbol: | PINX1 |
| NCBI Official Synonym Symbols: | LPTL; LPTS |
| NCBI Protein Information: | PIN2/TERF1-interacting telomerase inhibitor 1 |
| UniProt Protein Name: | PIN2/TERF1-interacting telomerase inhibitor 1 |
| UniProt Synonym Protein Names: | Liver-related putative tumor suppressor; Pin2-interacting protein X1; Protein 67-11-3; TRF1-interacting protein 1 |
| Protein Family: | PIN2/TERF1-interacting telomerase inhibitor |
| UniProt Gene Name: | PINX1 |
| UniProt Entry Name: | PINX1_HUMAN |
