Description
| 抗体名: | PDXK Antibody (PACO11155) |
| 抗体コード: | PACO11155 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human PDXK |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | pyridoxal (pyridoxine, vitamin B6) kinase;PDXK;C21orf124;C21orf97;DKFZp566A071;FLJ31940;FLJ37311;MGC15873;MGC31754;MGC52346;PKH;PNK;PRED79 ; |
| UniProt Protein Function: | PDXK: Required for synthesis of pyridoxal-5-phosphate from vitamin B6. Belongs to the pyridoxine kinase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Kinase, other; Cofactor and Vitamin Metabolism - vitamin B6; EC 2.7.1.35 Chromosomal Location of Human Ortholog: 21q22.3 Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus Molecular Function:ATP binding; lithium ion binding; magnesium ion binding; potassium ion binding; protein homodimerization activity; pyridoxal kinase activity; pyridoxal phosphate binding; sodium ion binding; zinc ion binding Biological Process: cell proliferation; pyridoxal 5'-phosphate salvage; pyridoxal phosphate biosynthetic process; vitamin B6 metabolic process |
| NCBI Summary: | The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O00764 |
| NCBI GenInfo Identifier: | 2811007 |
| NCBI Gene ID: | 8566 |
| NCBI Accession: | O00764.1 |
| UniProt Secondary Accession: | O00764,Q7Z2Y0, Q9BS02, |
| UniProt Related Accession: | O00764 |
| Molecular Weight: | 26,827 Da |
| NCBI Full Name: | Pyridoxal kinase |
| NCBI Synonym Full Names: | pyridoxal (pyridoxine, vitamin B6) kinase |
| NCBI Official Symbol: | PDXK |
| NCBI Official Synonym Symbols: | PKH; PNK; PRED79; C21orf97; HEL-S-1a; C21orf124 |
| NCBI Protein Information: | pyridoxal kinase |
| UniProt Protein Name: | Pyridoxal kinase |
| UniProt Synonym Protein Names: | Pyridoxine kinase |
| Protein Family: | Pyridoxine kinase |
| UniProt Gene Name: | PDXK |
| UniProt Entry Name: | PDXK_HUMAN |
