Description
| 抗体名: | PDE4C Antibody |
| 抗体コード: | PACO03280 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | WB:1:500-1:2000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the Internal region of human PDE4C. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | PDE4C; DPDE1; cAMP-specific 3'; 5'-cyclic phosphodiesterase 4C; DPDE1; PDE21 |
| UniProt Protein Function: | PDE4C: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. 7 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Phosphodiesterase; EC 3.1.4.53; Nucleotide Metabolism - purine Chromosomal Location of Human Ortholog: 19p13.11 Cellular Component: cytosol; extracellular space Molecular Function:3',5'-cyclic-AMP phosphodiesterase activity |
| NCBI Summary: | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] |
| UniProt Code: | Q08493 |
| NCBI GenInfo Identifier: | 20141263 |
| NCBI Gene ID: | 5143 |
| NCBI Accession: | Q08493.2 |
| UniProt Secondary Accession: | Q08493,Q9UN44, Q9UN45, Q9UN46, Q9UPJ6, B3KTC4, |
| UniProt Related Accession: | Q08493 |
| Molecular Weight: | – Da |
| NCBI Full Name: | cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
| NCBI Synonym Full Names: | phosphodiesterase 4C |
| NCBI Official Symbol: | PDE4C |
| NCBI Official Synonym Symbols: | DPDE1 |
| NCBI Protein Information: | cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
| UniProt Protein Name: | cAMP-specific 3',5'-cyclic phosphodiesterase 4C |
| UniProt Synonym Protein Names: | DPDE1; PDE21 |
| Protein Family: | cAMP-specific 3',5'-cyclic phosphodiesterase |
| UniProt Gene Name: | PDE4C |
| UniProt Entry Name: | PDE4C_HUMAN |
