| UniProt Protein Function: | PARP10: May play a role in cell proliferation. May be required for the maintenance of cell cycle progression. |
| UniProt Protein Details: | Protein type:EC 2.4.2.30; Transferase; Nucleolus Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: cytoplasm; Golgi apparatus; nucleoplasm; nucleus Molecular Function:NAD+ ADP-ribosyltransferase activity; protein binding Biological Process: inhibition of NF-kappaB transcription factor; negative regulation of fibroblast proliferation; negative regulation of protein import into nucleus, translocation; negative regulation of viral genome replication; protein amino acid ADP-ribosylation |
| NCBI Summary: | Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q53GL7 |
| NCBI GenInfo Identifier: | 116248563 |
| NCBI Gene ID: | 84875 |
| NCBI Accession: | Q53GL7.2 |
| UniProt Secondary Accession: | Q53GL7,Q8N2I0, Q8WV05, Q96CH7, Q96K72, |
| UniProt Related Accession: | Q53GL7 |
| Molecular Weight: | 109998 Da |
| NCBI Full Name: | Poly |
| NCBI Synonym Full Names: | poly(ADP-ribose) polymerase family member 10 |
| NCBI Official Symbol: | PARP10 |
| NCBI Official Synonym Symbols: | ARTD10 |
| NCBI Protein Information: | poly [ADP-ribose] polymerase 10 |
| UniProt Protein Name: | Poly [ADP-ribose] polymerase 10 |
| UniProt Synonym Protein Names: | ADP-ribosyltransferase diphtheria toxin-like 10; ARTD10 |
| Protein Family: | Poly [ADP-ribose] polymerase |
| UniProt Gene Name: | PARP10 |
| UniProt Entry Name: | PAR10_HUMAN |