Description
OTOR Antibody (PACO20145)
The OTOR Polyclonal Antibody (PAC020145) is a crucial tool for researchers studying OTOR, a novel protein implicated in various cellular functions. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for Western blot applications. By binding to the OTOR protein, this antibody enables accurate detection and analysis in a wide range of cell types.OTOR, also known as a potential tumor suppressor, is involved in regulating cellular processes such as cell proliferation, apoptosis, and differentiation. Its role in cancer development and progression makes it an attractive target for further investigation in oncology research.
By understanding the functions of OTOR, researchers can potentially uncover new therapeutic strategies for combating cancer and other related diseases.Overall, the OTOR Polyclonal Antibody is a valuable tool for researchers interested in uncovering the biological mechanisms underlying OTOR's functions and its involvement in disease development. Its high reactivity and specificity make it a reliable choice for studies in cancer biology and other related fields.
| Antibody Name: | OTOR Antibody (PACO20145) |
| Antibody SKU: | PACO20145 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human OTOR |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO20145(OTOR Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO20145(OTOR Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a member of the melanoma-inhibiting activity gene family. The encoded protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. |
| Synonyms: | otoraplin |
| UniProt Protein Function: | OTOR: is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. This gene is a member of the melanoma-inhibiting activity gene family. In addition, alternate polyA sites exist for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20p12.1-p11.23 Cellular Component: extracellular region Biological Process: sensory perception of sound; cartilage condensation |
| NCBI Summary: | This gene encodes a member of the melanoma-inhibiting activity gene family. The encoded protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9NRC9 |
| NCBI GenInfo Identifier: | 13124388 |
| NCBI Gene ID: | 56914 |
| NCBI Accession: | Q9NRC9.1 |
| UniProt Secondary Accession: | Q9NRC9,Q3MIU6, D3DW22, |
| UniProt Related Accession: | Q9NRC9 |
| Molecular Weight: | 14,332 Da |
| NCBI Full Name: | Otoraplin |
| NCBI Synonym Full Names: | otoraplin |
| NCBI Official Symbol: | OTOR |
| NCBI Official Synonym Symbols: | FDP; MIAL1 |
| NCBI Protein Information: | otoraplin; fibrocyte-derived protein; melanoma inhibitory activity-like protein |
| UniProt Protein Name: | Otoraplin |
| UniProt Synonym Protein Names: | Fibrocyte-derived protein; Melanoma inhibitory activity-like protein |
| Protein Family: | Otoraplin |
| UniProt Gene Name: | OTOR |
| UniProt Entry Name: | OTOR_HUMAN |
