The OFCC1 Polyclonal Antibody (PAC037642) is a valuable tool for researchers studying OFCC1, a protein involved in cell function regulation. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the OFCC1 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it ideal for investigations in immunology and cancer research.
OFCC1 is known for its role in regulating cellular processes and signaling pathways, making it an important target for studies on various diseases such as cancer, autoimmune disorders, and inflammatory conditions. By understanding the function of OFCC1, researchers can develop potential therapies that target or modulate its activity, providing new insights into the treatment of these diseases.
Antibody Name:
OFCC1 Antibody (PACO37642)
Antibody SKU:
PACO37642
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human, Mouse
Immunogen:
Recombinant Human Orofacial cleft 1 candidate gene 1 protein (3-231AA)
Western blot. All lanes: OFCC1 antibody at 2µg/ml + Mouse gonadal tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 27, 32, 21, 14, 16 kDa. Observed band size: 27 kDa.
Background:
This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG).
Synonyms:
Orofacial cleft 1 candidate gene 1 protein (Orofacial clefting chromosomal breakpoint region candidate 1 protein), OFCC1, MRDS1
UniProt Protein Function:
OFCC1: A chromosomal aberration involving OFCC1 is found in patients with orofacial cleft. 5 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 6p24.3Molecular Function: protein binding
