| UniProt Protein Function: | NUTF2: Facilitates protein transport into the nucleus. Interacts with the nucleoporin p62 and with Ran. Acts at a relatively late stage of nuclear protein import, subsequent to the initial docking of nuclear import ligand at the nuclear envelope. Could be part of a multicomponent system of cytosolic factors that assemble at the pore complex during nuclear import. Homodimer. |
| UniProt Protein Details: | Protein type:Nuclear import Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: cytosol; nuclear outer membrane; nuclear pore Molecular Function:protein binding; Ran GTPase binding; transporter activity Biological Process: positive regulation of protein import into nucleus; protein export from nucleus; protein import into nucleus, translocation |
| NCBI Summary: | This gene encodes a cytosolic factor that facilitates protein transport into the nucleus. The encoded protein is required for nuclear import of the small Ras-like GTPase, Ran which is involved in numerous cellular processes. This protein also interacts with the nuclear pore complex glycoprotein p62. [provided by RefSeq, Apr 2016] |
| UniProt Code: | P61970 |
| NCBI GenInfo Identifier: | 48429030 |
| NCBI Gene ID: | 10204 |
| NCBI Accession: | P61970.1 |
| UniProt Secondary Accession: | P61970,P13662, Q6IB67, B2R4G7, |
| UniProt Related Accession: | P61970 |
| Molecular Weight: | 14,478 Da |
| NCBI Full Name: | Nuclear transport factor 2 |
| NCBI Synonym Full Names: | nuclear transport factor 2 |
| NCBI Official Symbol: | NUTF2 |
| NCBI Official Synonym Symbols: | NTF2; PP15; NTF-2 |
| NCBI Protein Information: | nuclear transport factor 2 |
| UniProt Protein Name: | Nuclear transport factor 2 |
| UniProt Synonym Protein Names: | Placental protein 15; PP15 |
| UniProt Gene Name: | NUTF2 |
| UniProt Entry Name: | NTF2_HUMAN |
