Description
| 抗体名: | NR2F2 Antibody |
| 抗体コード: | PACO00427 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | synthesized peptide derived from the N-terminal region of human ARP-1. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | NR2F2; ARP1; TFCOUP2; COUP transcription factor 2; COUP-TF2; Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2 |
| UniProt Protein Function: | NR2F2: Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. Interacts with SQSTM1. Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2. Ubiquitous. Belongs to the nuclear hormone receptor family. NR2 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding; Motility/polarity/chemotaxis; Nuclear receptor Chromosomal Location of Human Ortholog: 15q26.2 Cellular Component: nucleus Molecular Function:ligand-dependent nuclear receptor activity; protein binding; protein homodimerization activity; retinoic acid binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activity Biological Process: lipid metabolic process; negative regulation of cyclin-dependent protein kinase activity; negative regulation of endothelial cell proliferation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; signal transduction Disease: Congenital Heart Defects, Multiple Types, 4 |
| NCBI Summary: | This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| UniProt Code: | P24468 |
| NCBI GenInfo Identifier: | 114203 |
| NCBI Gene ID: | 7026 |
| NCBI Accession: | P24468.1 |
| UniProt Secondary Accession: | P24468,Q03754, Q3KQR7, B4DQJ2, B6ZGU1, |
| UniProt Related Accession: | P24468 |
| Molecular Weight: | 46kDa |
| NCBI Full Name: | COUP transcription factor 2 |
| NCBI Synonym Full Names: | nuclear receptor subfamily 2 group F member 2 |
| NCBI Official Symbol: | NR2F2 |
| NCBI Official Synonym Symbols: | ARP1; CHTD4; NF-E3; NR2F1; SVP40; COUPTFB; TFCOUP2; COUPTFII |
| NCBI Protein Information: | COUP transcription factor 2 |
| UniProt Protein Name: | COUP transcription factor 2 |
| UniProt Synonym Protein Names: | Apolipoprotein A-I regulatory protein 1; ARP-1; COUP transcription factor II; COUP-TF II; Nuclear receptor subfamily 2 group F member 2 |
| Protein Family: | COUP transcription factor |
| UniProt Gene Name: | NR2F2 |
