Description
| 抗体名: | NPFFR2 Antibody, FITC conjugated (PACO63933) |
| 抗体コード: | PACO63933 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA |
| 推奨される希釈: | |
| 反応性: | Human |
| 免疫原: | Peptide sequence from Human Neuropeptide FF receptor 2 protein (23-43AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | FITC |
| バックグラウンド: | Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
| シノニム: | Neuropeptide FF receptor 2 (G-protein coupled receptor 74) (G-protein coupled receptor HLWAR77) (Neuropeptide G-protein coupled receptor), NPFFR2, GPR74 NPFF2 NPGPR |
| UniProt Protein Function: | NPFFR2: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 4q21 Cellular Component: actin cytoskeleton; integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; neuropeptide receptor activity; peptide binding Biological Process: cellular response to hormone stimulus; detection of abiotic stimulus; G-protein coupled receptor protein signaling pathway; synaptic transmission |
| NCBI Summary: | This gene encodes a member of a subfamily of G-protein-coupled neuropeptide receptors. This protein is activated by the neuropeptides A-18-amide (NPAF) and F-8-amide (NPFF) and may function in pain modulation and regulation of the opioid system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
| UniProt Code: | Q9Y5X5 |
| NCBI GenInfo Identifier: | 13878604 |
| NCBI Gene ID: | 10886 |
| NCBI Accession: | Q9Y5X5.2 |
| UniProt Secondary Accession: | Q9Y5X5,Q96RV1, Q9NR49, |
| UniProt Related Accession: | Q9Y5X5 |
| Molecular Weight: | 15,055 Da |
| NCBI Full Name: | Neuropeptide FF receptor 2 |
| NCBI Synonym Full Names: | neuropeptide FF receptor 2 |
| NCBI Official Symbol: | NPFFR2 |
| NCBI Official Synonym Symbols: | GPR74; NPFF2; NPGPR; HLWAR77 |
| NCBI Protein Information: | neuropeptide FF receptor 2 |
| UniProt Protein Name: | Neuropeptide FF receptor 2 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 74; G-protein coupled receptor HLWAR77; Neuropeptide G-protein coupled receptor |
| Protein Family: | Neuropeptide FF receptor |
| UniProt Gene Name: | NPFFR2 |
| UniProt Entry Name: | NPFF2_HUMAN |
