| UniProt Protein Function: | NMI: May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5. Belongs to the NMI family. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 2q23.3 Cellular Component: cytoplasm; cytosol; nucleoplasm Molecular Function:identical protein binding; protein binding Biological Process: inflammatory response; JAK-STAT cascade |
| NCBI Summary: | NMYC interactor (NMI) encodes a protein that interacts with NMYC and CMYC (two members of the oncogene Myc family), and other transcription factors containing a Zip, HLH, or HLH-Zip motif. The NMI protein also interacts with all STATs except STAT2 and augments STAT-mediated transcription in response to cytokines IL2 and IFN-gamma. The NMI mRNA has low expression levels in all human fetal and adult tissues tested except brain and has high expression in cancer cell line-myeloid leukemias. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13287 |
| NCBI GenInfo Identifier: | 116242679 |
| NCBI Gene ID: | 9111 |
| NCBI Accession: | Q13287.2 |
| UniProt Secondary Accession: | Q13287,Q53TI8, Q8WTW2, Q9BVE5, B5BU69, |
| UniProt Related Accession: | Q13287 |
| Molecular Weight: | 35kDa |
| NCBI Full Name: | N-myc-interactor |
| NCBI Synonym Full Names: | N-myc and STAT interactor |
| NCBI Official Symbol: | NMI |
| NCBI Protein Information: | N-myc-interactor |
| UniProt Protein Name: | N-myc-interactor |
| UniProt Synonym Protein Names: | N-myc and STAT interactor |
| Protein Family: | N-myc-interactor |
| UniProt Gene Name: | NMI |
