Description
| 抗体名: | NKRF Antibody (PACO10863) |
| 抗体コード: | PACO10863 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human NKRF |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | NFKB repressing factor;NKRF;ITBA4;NRF ; |
| UniProt Protein Function: | NKRF: Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription. |
| UniProt Protein Details: | Protein type:Nucleolus; RNA-binding; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: Xq24 Cellular Component: endoplasmic reticulum; nucleolus; nucleus Molecular Function:protein binding; DNA binding Biological Process: transcription, DNA-dependent; negative regulation of transcription, DNA-dependent |
| NCBI Summary: | This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] |
| UniProt Code: | O15226 |
| NCBI GenInfo Identifier: | 33860178 |
| NCBI Gene ID: | 55922 |
| NCBI Accession: | O15226.2 |
| UniProt Secondary Accession: | O15226,Q4VC41, Q9UJ91, G3V1N1, |
| UniProt Related Accession: | O15226 |
| Molecular Weight: | 690 |
| NCBI Full Name: | NF-kappa-B-repressing factor |
| NCBI Synonym Full Names: | NFKB repressing factor |
| NCBI Official Symbol: | NKRF |
| NCBI Official Synonym Symbols: | NRF; ITBA4 |
| NCBI Protein Information: | NF-kappa-B-repressing factor; transcription factor NRF |
| UniProt Protein Name: | NF-kappa-B-repressing factor |
| UniProt Synonym Protein Names: | Protein ITBA4; Transcription factor NRF |
| Protein Family: | NF-kappa-B-repressing factor |
| UniProt Gene Name: | NKRF |
| UniProt Entry Name: | NKRF_HUMAN |
