Description
| 抗体名: | NKIRAS1 Antibody (PACO41998) |
| 抗体コード: | PACO41998 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| 反応性: | Human |
| 免疫原: | Recombinant Human NF-kappa-B inhibitor-interacting Ras-like protein 1 protein (1-192AA) |
| 憲法: | Liquid |
| ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| 精製方法: | >95%, Protein G purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: NKIRAS1 antibody at 7µg/ml + HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 22 kDa. Observed band size: 22 kDa. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO41998 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO41998 at dilution of 1:100. |
| バックグラウンド: | Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor β (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. |
| シノニム: | NF-kappa-B inhibitor-interacting Ras-like protein 1 (I-kappa-B-interacting Ras-like protein 1) (κ B-Ras protein 1) (KappaB-Ras1), NKIRAS1, KBRAS1 |
| UniProt Protein Function: | NKIRAS1: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB. Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. |
| UniProt Protein Details: | Protein type:G protein, monomeric, Ras; G protein; G protein, monomeric Chromosomal Location of Human Ortholog: 3p24.2 |
| UniProt Code: | Q9NYS0 |
| NCBI GenInfo Identifier: | 74753075 |
| NCBI Gene ID: | 28512 |
| NCBI Accession: | Q9NYS0.1 |
| UniProt Secondary Accession: | Q9NYS0,Q96K18, |
| UniProt Related Accession: | Q9NYS0 |
| Molecular Weight: | 21,643 Da |
| NCBI Full Name: | NF-kappa-B inhibitor-interacting Ras-like protein 1 |
| NCBI Synonym Full Names: | NFKB inhibitor interacting Ras like 1 |
| NCBI Official Symbol: | NKIRAS1 |
| NCBI Official Synonym Symbols: | KBRAS1; kappaB-Ras1 |
| NCBI Protein Information: | NF-kappa-B inhibitor-interacting Ras-like protein 1 |
| UniProt Protein Name: | NF-kappa-B inhibitor-interacting Ras-like protein 1 |
| UniProt Synonym Protein Names: | I-kappa-B-interacting Ras-like protein 1; Kappa B-Ras protein 1; KappaB-Ras1 |
| Protein Family: | NF-kappa-B inhibitor-interacting Ras-like protein |
| UniProt Gene Name: | NKIRAS1 |
| UniProt Entry Name: | KBRS1_HUMAN |
| Antibodies |
| Anti-NKIRAS1 Antibody (CAB14878) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
