| UniProt Protein Function: | NINJ1: Homophilic cell adhesion molecule that promotes axonal growth. May play a role in nerve regeneration and in the formation and function of other tissues. Cell adhesion requires divalent cations. Belongs to the ninjurin family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Cell development/differentiation; Cell adhesion; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 9q22 Cellular Component: integral to membrane Biological Process: nervous system development; tissue regeneration; cell adhesion; positive regulation of cell-matrix adhesion |
| NCBI Summary: | The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt, 1996 [PubMed 8780658]). It demonstrates properties of a homophilic adhesion molecule and promotes neurite outgrowth from primary cultured dorsal root ganglion neurons.[supplied by OMIM, Aug 2009] |
| UniProt Code: | Q92982 |
| NCBI GenInfo Identifier: | 148922911 |
| NCBI Gene ID: | 4814 |
| NCBI Accession: | NP_004139 |
| UniProt Secondary Accession: | Q92982,Q6GU89, Q8WUV5, Q9BT07, |
| UniProt Related Accession: | Q92982 |
| Molecular Weight: | Predicted: 17 kDaObserved: 16 kDa |
| NCBI Full Name: | ninjurin-1 |
| NCBI Synonym Full Names: | ninjurin 1 |
| NCBI Official Symbol: | NINJ1 |
| NCBI Official Synonym Symbols: | NIN1; NINJURIN |
| NCBI Protein Information: | ninjurin-1; nerve injury-induced protein 1; nerve injury-induced protein-1 |
| UniProt Protein Name: | Ninjurin-1 |
| UniProt Synonym Protein Names: | Nerve injury-induced protein 1 |
| Protein Family: | Ninjurin |
| UniProt Gene Name: | NINJ1 |
| UniProt Entry Name: | NINJ1_HUMAN |
