Description
| 抗体名: | NFATC2IP Antibody (PACO05543) |
| 抗体コード: | PACO05543 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB |
| 推奨される希釈: | ELISA:1:10000, WB:1:500-1:2000 |
| 反応性: | Human |
| 免疫原: | Synthesized peptide derived from the Internal region of human NFATc2IP. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | NFATC2IP; NIP45; NFATC2-interacting protein; 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells; cytoplasmic 2-interacting protein |
| UniProt Protein Function: | NFATC2IP: In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'- methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: cytoplasm; nucleus Biological Process: cytokine production; positive regulation of transcription from RNA polymerase II promoter |
| UniProt Code: | Q8NCF5 |
| NCBI GenInfo Identifier: | 51873914 |
| NCBI Gene ID: | 84901 |
| NCBI Accession: | AAH80628.1 |
| UniProt Secondary Accession: | Q8NCF5,O09130, Q6AYG7, |
| UniProt Related Accession: | Q8NCF5 |
| Molecular Weight: | 45,817 Da |
| NCBI Full Name: | NFATC2IP protein, partial |
| NCBI Synonym Full Names: | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein |
| NCBI Official Symbol: | NFATC2IP |
| NCBI Official Synonym Symbols: | ESC2; NIP45; RAD60 |
| NCBI Protein Information: | NFATC2-interacting protein; 45 kDa NFAT-interacting protein; 45 kDa NF-AT-interacting protein; nuclear factor of activated T-cells, cytoplasmic 2-interacting protein |
| UniProt Protein Name: | NFATC2-interacting protein |
| UniProt Synonym Protein Names: | 45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein |
| UniProt Gene Name: | NFATC2IP |
| UniProt Entry Name: | NF2IP_HUMAN |
