NDUFV2 Antibody (PACO10800)

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SKU:
PACO10800
Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Application:
ELISA
Application:
WB
Application:
IHC
Application:
IF
Antibody type:
Polyclonal
Conjugation:
Unconjugated
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Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:NDUFV2 Antibody (PACO10800)
抗体コード:PACO10800
サイズ:50ul
宿主種:Rabbit
申し込み:ELISA, WB, IHC, IF
推奨される希釈:
反応性:Human, Mouse, Rat
免疫原:Human NDUFV2
憲法:Liquid
ストレージバッファ:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
精製方法:Antigen Affinity purified
抗体のクローン性:Polyclonal
アイソタイプ:IgG
Conjugate:Non-conjugated
シノニム:NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa;
UniProt Protein Function:NDUFV2: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 24 kDa subunit family.
UniProt Protein Details:

Protein type:Oxidoreductase; Mitochondrial; EC 1.6.99.3; EC 1.6.5.3; Energy Metabolism - oxidative phosphorylation

Chromosomal Location of Human Ortholog: 18p11.22

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex I

Molecular Function:2 iron, 2 sulfur cluster binding; electron carrier activity; NADH dehydrogenase (ubiquinone) activity; metal ion binding

Biological Process: cardiac muscle development; cellular metabolic process; nervous system development; mitochondrial electron transport, NADH to ubiquinone

Disease: Mitochondrial Complex I Deficiency

NCBI Summary:The NADH-ubiquinone oxidoreductase complex (complex I) of the mitochondrial respiratory chain catalyzes the transfer of electrons from NADH to ubiquinone, and consists of at least 43 subunits. The complex is located in the inner mitochondrial membrane. This gene encodes the 24 kDa subunit of complex I, and is involved in electron transfer. Mutations in this gene are implicated in Parkinson's disease, bipolar disorder, schizophrenia, and have been found in one case of early onset hypertrophic cardiomyopathy and encephalopathy. A non-transcribed pseudogene of this locus is found on chromosome 19. [provided by RefSeq, Oct 2009]
UniProt Code:P19404
NCBI GenInfo Identifier:20455499
NCBI Gene ID:4729
NCBI Accession:P19404.2
UniProt Secondary Accession:P19404,Q9BV41,
UniProt Related Accession:P19404
Molecular Weight:249
NCBI Full Name:NADH dehydrogenase
NCBI Synonym Full Names:NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NCBI Official Symbol:NDUFV2  
NCBI Official Synonym Symbols:CI-24k  
NCBI Protein Information:NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial; complex I 24kDa subunit; NADH-ubiquinone oxidoreductase 24 kDa subunit; NADH-ubiquinone oxidoreductase flavoprotein 2; complex I, mitochondrial respitory chain, 24 kD subunit; NADH dehydrogenase ubiquinone flavoprotein 2, mitochondrial; nuclear-encoded mitochondrial NADH-ubiquinone reductase 24Kd subunit
UniProt Protein Name:NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial
UniProt Synonym Protein Names:NADH-ubiquinone oxidoreductase 24 kDa subunit
Protein Family:NADH dehydrogenase [ubiquinone] flavoprotein
UniProt Gene Name:NDUFV2  
UniProt Entry Name:NDUV2_HUMAN
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