Description
| 抗体名: | NDE1 Antibody (PACO10768) |
| 抗体コード: | PACO10768 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC, IF |
| 推奨される希釈: | |
| 反応性: | Human, Mouse, Rat |
| 免疫原: | Human NDE1 |
| 憲法: | Liquid |
| ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| 精製方法: | Antigen Affinity Purified |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
| シノニム: | nudE nuclear distribution gene E homolog 1 (A. nidulans);NDE1;FLJ20101;HOM-TES-87;NUDE;NUDE1 ; |
| UniProt Protein Function: | NUDE1: a microtubule-associated protein required for centrosome duplication, and the formation and function of the mitotic spindle. Associated with the centrosome, kinetochore, and spindle. Specifically phosphorylated during M phase, inducing its association with mitotic spindles. Appears to participate in dynein-mediated transport of kinetochore proteins to spindle poles along microtubules. Interacts with gamma tubulin, dynactin, CEP110, dynein,TCP1. PAFAH1B1, PCM-1 and PCNT. Concentrates at the plus ends of microtubules coincident with kinetochores in metaphase and anaphase, and at the cleavage furrow during cytokinesis.Two alternatively spliced human isoforms have been described. |
| UniProt Protein Details: | Protein type:Microtubule-binding; Cell cycle regulation; Cytoskeletal Chromosomal Location of Human Ortholog: 16p13.11 Cellular Component: kinetochore; centrosome; kinesin complex; microtubule; membrane; spindle pole centrosome; cytosol; cleavage furrow Molecular Function:protein domain specific binding; identical protein binding; protein binding; microtubule binding Biological Process: cell migration; organelle organization and biogenesis; establishment of chromosome localization; neuron migration; microtubule nucleation; chromosome segregation; mitotic centrosome separation; centrosome localization; establishment of mitotic spindle orientation; cell division; neuroblast proliferation; vesicle transport along microtubule; mitotic cell cycle; cerebral cortex development; G2/M transition of mitotic cell cycle; centrosome duplication Disease: Lissencephaly 4; Microhydranencephaly |
| UniProt Code: | Q9NXR1 |
| NCBI GenInfo Identifier: | 108860813 |
| NCBI Gene ID: | |
| NCBI Accession: | Q9NXR1.2 |
| Molecular Weight: | 37kDa; 38kDa |
| NCBI Full Name: | Nuclear distribution protein nudE homolog 1 |
| UniProt Protein Name: | Nuclear distribution protein nudE homolog 1 |
| Protein Family: | Nuclear distribution protein |
| UniProt Gene Name: | NDE1 |
| UniProt Entry Name: | NDE1_HUMAN |
